BDBM645374 US11873292, Compound A34::trans-N-(piperidin-4-ylmethyl)-2- (1-(4-(trifluoromethyl)benzenesulfonyl) indolin-5-yl)cyclopropylamine

SMILES FC(F)(F)c1ccc(cc1)S(=O)(=O)N1CCc2cc(ccc12)C1CC1NCC1CCNCC1

InChI Key InChIKey=ZEGOQEFCQGFPOF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 645374   

TargetLysine-specific histone demethylase 1A(Human)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM645374(trans-N-(piperidin-4-ylmethyl)-2- (1-(4-(trifluoro...)
Affinity DataIC50: 43.3nMAssay Description:Principle: LSD1 specifically removes the methylation modification at K4 lysine on H3 polypeptide substrate, making it a substrate without methylation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2024
Entry Details
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TargetAmine oxidase [flavin-containing] A(Human)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM645374(trans-N-(piperidin-4-ylmethyl)-2- (1-(4-(trifluoro...)
Affinity DataIC50: 1.00E+5nMAssay Description:Principle: A specific luciferin derivative was used as a substrate. MAOA or MAOB can catalyze the conversion of substrate to luciferin methyl ester. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2024
Entry Details
Go to US Patent

TargetAmine oxidase [flavin-containing] B(Human)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM645374(trans-N-(piperidin-4-ylmethyl)-2- (1-(4-(trifluoro...)
Affinity DataIC50: 1.00E+5nMAssay Description:Principle: A specific luciferin derivative was used as a substrate. MAOA or MAOB can catalyze the conversion of substrate to luciferin methyl ester. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2024
Entry Details
Go to US Patent