BDBM645371 Trans-tert-butyl 4-(2-(1-(phenylsulfonyl)indolin-5- yl)cyclopropylcarbamoyl)piperidine- 1-carboxylate::US11873292, Compound A29

SMILES CC(C)(C)OC(=O)N1CCC(CC1)C(=O)NC1CC1c1ccc2N(CCc2c1)S(=O)(=O)c1ccccc1

InChI Key InChIKey=FZJPNTFTXQAASV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 645371   

TargetLysine-specific histone demethylase 1A(Human)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM645371(Trans-tert-butyl 4-(2-(1-(phenylsulfonyl)indolin-5...)
Affinity DataIC50: 1.69E+3nMAssay Description:Principle: LSD1 specifically removes the methylation modification at K4 lysine on H3 polypeptide substrate, making it a substrate without methylation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2024
Entry Details
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