BDBM645369 Trans-tert-butyl 4-((2-(1-(phenylsulfonyl)indolin-5- yl)cyclopropylamino)methyl) piperidine-1-carboxylate::US11873292, Compound A27

SMILES CC(C)(C)OC(=O)N1CCC(CNC2CC2c2ccc3N(CCc3c2)S(=O)(=O)c2ccccc2)CC1

InChI Key InChIKey=DXDDLSVKQIJIKQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 645369   

TargetLysine-specific histone demethylase 1A(Human)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM645369(Trans-tert-butyl 4-((2-(1-(phenylsulfonyl)indolin-...)
Affinity DataIC50: 71.3nMAssay Description:Principle: LSD1 specifically removes the methylation modification at K4 lysine on H3 polypeptide substrate, making it a substrate without methylation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2024
Entry Details
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TargetAmine oxidase [flavin-containing] A(Human)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM645369(Trans-tert-butyl 4-((2-(1-(phenylsulfonyl)indolin-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Principle: A specific luciferin derivative was used as a substrate. MAOA or MAOB can catalyze the conversion of substrate to luciferin methyl ester. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2024
Entry Details
Go to US Patent

TargetAmine oxidase [flavin-containing] B(Human)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM645369(Trans-tert-butyl 4-((2-(1-(phenylsulfonyl)indolin-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Principle: A specific luciferin derivative was used as a substrate. MAOA or MAOB can catalyze the conversion of substrate to luciferin methyl ester. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2024
Entry Details
Go to US Patent