BDBM645363 US11873292, Compound A19::trans-N1-(2-(1-(phenylsulfonyl) indolin-5-yl)cyclopropyl) cyclohexane-1,4-diamine

SMILES NC1CCC(CC1)NC1CC1c1ccc2N(CCc2c1)S(=O)(=O)c1ccccc1

InChI Key InChIKey=AOKTYMNPAGJHMH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 645363   

TargetLysine-specific histone demethylase 1A(Human)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM645363(trans-N1-(2-(1-(phenylsulfonyl) indolin-5-yl)cyclo...)
Affinity DataIC50: 62.9nMAssay Description:Principle: LSD1 specifically removes the methylation modification at K4 lysine on H3 polypeptide substrate, making it a substrate without methylation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2024
Entry Details
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TargetAmine oxidase [flavin-containing] A(Human)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM645363(trans-N1-(2-(1-(phenylsulfonyl) indolin-5-yl)cyclo...)
Affinity DataIC50: 1.00E+5nMAssay Description:Principle: A specific luciferin derivative was used as a substrate. MAOA or MAOB can catalyze the conversion of substrate to luciferin methyl ester. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2024
Entry Details
Go to US Patent

TargetAmine oxidase [flavin-containing] B(Human)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM645363(trans-N1-(2-(1-(phenylsulfonyl) indolin-5-yl)cyclo...)
Affinity DataIC50: 1.00E+5nMAssay Description:Principle: A specific luciferin derivative was used as a substrate. MAOA or MAOB can catalyze the conversion of substrate to luciferin methyl ester. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2024
Entry Details
Go to US Patent