BDBM645227 6-(2-(bicyclo[1.1.1]pentan-1- ylamino)pyrimidin-5-yl)-2-((5- fluoropyridin-3- yl)methyl)pyridazine-3(2H)-one::US11873290, Compound 64

SMILES Fc1cncc(Cn2nc(ccc2=O)-c2cnc(NC34CC(C3)C4)nc2)c1

InChI Key InChIKey=RJUPQEBOPLJTOL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 645227   

TargetDystrophin(Human)
Edgewise Therapeutics

US Patent
LigandPNGBDBM645227(US11873290, Compound 64 | 6-(2-(bicyclo[1.1.1]pent...)
Affinity DataIC50: 1.00E+4nMAssay Description:BSA, ATP, NADH, PEP, and DTT solutions were thawed at room temperature, then transferred to ice. Pellet-frozen myofibrils (approximately twice the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2024
Entry Details
Go to US Patent