BDBM645190 6-(6- (difluoromethoxy)pyridin- 3-yl)-2-((5-phenyl-1,3,4- thiadiazol-2-yl)methyl)pyridazin- 3(2H)-one::US11873290, Compound 22

SMILES FC(F)Oc1ccc(cn1)-c1ccc(=O)n(Cc2nnc(s2)-c2ccccc2)n1

InChI Key InChIKey=BAKKURMYVIENCZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 645190   

TargetDystrophin(Human)
Edgewise Therapeutics

US Patent
LigandPNGBDBM645190(US11873290, Compound 22 | 6-(6- (difluoromethoxy)p...)
Affinity DataIC50: 1.00E+4nMAssay Description:BSA, ATP, NADH, PEP, and DTT solutions were thawed at room temperature, then transferred to ice. Pellet-frozen myofibrils (approximately twice the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2024
Entry Details
Go to US Patent

TargetDystrophin(Human)
Edgewise Therapeutics

US Patent
LigandPNGBDBM645190(US11873290, Compound 22 | 6-(6- (difluoromethoxy)p...)
Affinity DataIC50: 1.00E+5nMAssay Description:Following example 15, the counter screen was done using frozen myofibril pellets obtained from cardiac tissue. The assay was done in the same manner ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2024
Entry Details
Go to US Patent