BDBM645104 US20240010684, Ex. No 81

SMILES CCCCN1C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@H]2SS[C@H](NC(=O)[C@H](NC(=O)[C@@H](NC(=O)CNC(=O)[C@@H](N)n3cc(C[C@H](NC(=O)[C@@H]4CCCN4C(=O)[C@@H](NC2=O)[C@@H](C)CC)C(N)=O)nn3)OC)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)(C)C)C(=O)N2CCC[C@H]2C1=O

InChI Key InChIKey=YISLGRHFFVCCJW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 645104   

TargetMannan-binding lectin serine protease 1(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM645104(US20240010684, Ex. No 81)
Affinity DataIC50: 18nMAssay Description:Recombinant human MASP1 enzyme produced in the HEK 293 cells was diluted in the reaction buffer (50 mM HEPES pH 8,0; 100 mM NaCl; 0,01% CHAPS; 0.5 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2024
Entry Details
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TargetMannan-binding lectin serine protease 2(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM645104(US20240010684, Ex. No 81)
Affinity DataIC50: 230nMAssay Description:Recombinant human MASP2 enzyme produced in the HEK 293 cells was diluted in the reaction buffer (50 mM HEPES pH 8,0; 100 mM NaCl; 0,01% CHAPS; 0.5 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2024
Entry Details
Go to US Patent