BDBM645099 US20240010684, Ex. No 76

SMILES CCCCN1C(=O)N[C@@H](CC(=O)NCCCCC(=O)NCC(=O)N(C)C(=O)NC([C@@H](C)CC)C(=O)N[C@H]2CSSC(C)(C)[C@H](NC(=O)[C@@H](NC(=O)[C@@H]3C[C@@H]4CCCC[C@@H]4N3C(=O)[C@@H]3CCCN3C(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CO)NC2=O)[C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C1=O)C(N)=O

InChI Key InChIKey=ARHYJCIBJJPJKC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 645099   

TargetMannan-binding lectin serine protease 1(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM645099(US20240010684, Ex. No 76)
Affinity DataIC50: 9.70nMAssay Description:Recombinant human MASP1 enzyme produced in the HEK 293 cells was diluted in the reaction buffer (50 mM HEPES pH 8,0; 100 mM NaCl; 0,01% CHAPS; 0.5 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2024
Entry Details
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TargetMannan-binding lectin serine protease 2(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM645099(US20240010684, Ex. No 76)
Affinity DataIC50: 180nMAssay Description:Recombinant human MASP2 enzyme produced in the HEK 293 cells was diluted in the reaction buffer (50 mM HEPES pH 8,0; 100 mM NaCl; 0,01% CHAPS; 0.5 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2024
Entry Details
Go to US Patent