BDBM645093 US20240010684, Ex. No 69

SMILES CCCCN1C(=O)CCCCNC(=O)[C@H](CC(C)(C)C)NC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CO)NC(=O)[C@H]2NC(=O)[C@@H](NC(=O)CNC(=O)[C@H]3CC[C@@H](CC3)NC(=O)NC(=O)[C@H](NC(=O)[C@@H]3CCCN3C(=O)[C@@H](NC(=O)[C@H](CSS2)N(C)C(=O)[C@@H](NC1=O)[C@@H](C)CC)[C@@H](C)CC)C(N)=O)[C@@H](C)CC

InChI Key InChIKey=LQRNULOTICMUKB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 645093   

TargetMannan-binding lectin serine protease 1(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM645093(US20240010684, Ex. No 69)
Affinity DataIC50: 20nMAssay Description:Recombinant human MASP1 enzyme produced in the HEK 293 cells was diluted in the reaction buffer (50 mM HEPES pH 8,0; 100 mM NaCl; 0,01% CHAPS; 0.5 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2024
Entry Details
Go to US Patent

TargetMannan-binding lectin serine protease 2(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM645093(US20240010684, Ex. No 69)
Affinity DataIC50: 190nMAssay Description:Recombinant human MASP2 enzyme produced in the HEK 293 cells was diluted in the reaction buffer (50 mM HEPES pH 8,0; 100 mM NaCl; 0,01% CHAPS; 0.5 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2024
Entry Details
Go to US Patent