BDBM645018 US11981682, Example 2-6::US20240010658, Example 2-6

SMILES CN(C)c1ncc(s1)C(=O)N1C[C@@H]2CC[C@@H](Nc3ccc(Br)nn3)[C@@H]2C1

InChI Key InChIKey=FPRUYTZIJVSTIQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 645018   

TargetMonoacylglycerol lipase ABHD6 [33-337](Human)
Ono Pharmaceutical Co.

US Patent
LigandPNGBDBM645018(US20240010658, Example 2-6 | US11981682, Example 2...)
Affinity DataIC50: 2nMAssay Description:First, 1-arachidonoyl glycerol (Cayman Chemical) as a substrate was prepared with an assay buffer containing 50 mM tris-HCl (pH 7.4), 100 mM NaCl, an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2024
Entry Details
Go to US Patent

TargetMonoacylglycerol lipase ABHD6(Human)
Ono Pharmaceutical Co.

US Patent
LigandPNGBDBM645018(US20240010658, Example 2-6 | US11981682, Example 2...)
Affinity DataIC50: 2nMAssay Description:First, 1-arachidonoyl glycerol (Cayman Chemical) as a substrate was prepared with an assay buffer containing 50 mM tris-HCl (pH 7.4), 100 mM NaCl, an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2024
Entry Details
Go to US Patent

TargetMonoacylglycerol lipase ABHD6(Human)
Ono Pharmaceutical Co.

US Patent
LigandPNGBDBM645018(US20240010658, Example 2-6 | US11981682, Example 2...)
Affinity DataIC50: 25nMAssay Description:The binding affinity of the test compound for human ABHD6 was measured using bioluminescence resonance energy transfer (hereinafter, abbreviated as B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2024
Entry Details
Go to US Patent