BDBM644952 US20240009175, Compound 59::[1-ethyl-5-methyl-6-(1H-1,2,3,4- tetrazol-5-yl)-1H-imidazo[4,5-b]pyridin- 2-yl]bis(2-fluorophenyl)methanol

SMILES CCn1c(nc2nc(C)c(cc12)-c1nnn[nH]1)C(O)(c1ccccc1F)c1ccccc1F

InChI Key InChIKey=INIFVODFCJGLBP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 644952   

TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Merck Patent

US Patent
LigandPNGBDBM644952(US20240009175, Compound 59 | [1-ethyl-5-methyl-6-(...)
Affinity DataIC50: 5.5nMAssay Description:The assay was performed in Perkin Elmer 384 well white Proxiplates in a total volume of 8 μl. 1 nM (fc)C-term myc tagged ACSS2 (human, recombina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2024
Entry Details
Go to US Patent