BDBM644913 US20240009175, Compound 20::[6-Chloro-3-ethyl-5-(1H-tetrazol-5-yl)- pyrazolo[1,5-a]pyridin-2-yl]-bis-(2-fluoro- phenyl)-methanol

SMILES CCc1c(nn2cc(Cl)c(cc12)-c1nnn[nH]1)C(O)(c1ccccc1F)c1ccccc1F

InChI Key InChIKey=OIVBVJDXBMBHCO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 644913   

TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Merck Patent

US Patent
LigandPNGBDBM644913(US20240009175, Compound 20 | [6-Chloro-3-ethyl-5-(...)
Affinity DataIC50: 5.5nMAssay Description:The assay was performed in Perkin Elmer 384 well white Proxiplates in a total volume of 8 μl. 1 nM (fc)C-term myc tagged ACSS2 (human, recombina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2024
Entry Details
Go to US Patent