BDBM644900 US20240009175, Compound 7::US20240009175, Compound 8::US20240009175, Compound 9::[7-chloro-3-ethyl-6-(1H-tetrazol-5- yl)imidazo[1,2-a]pyridin-2-yl]-phenyl-(2- pyridyl)methanol

SMILES CCc1c(nc2cc(Cl)c(cn12)-c1nnn[nH]1)C(O)(c1ccccc1)c1ccccn1

InChI Key InChIKey=IBURTJZVTZJPPN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 644900   

TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Merck Patent

US Patent
LigandPNGBDBM644900(US20240009175, Compound 8 | [7-chloro-3-ethyl-6-(1...)
Affinity DataIC50: 55nMAssay Description:The assay was performed in Perkin Elmer 384 well white Proxiplates in a total volume of 8 μl. 1 nM (fc)C-term myc tagged ACSS2 (human, recombina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2024
Entry Details
Go to US Patent

TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Merck Patent

US Patent
LigandPNGBDBM644900(US20240009175, Compound 8 | [7-chloro-3-ethyl-6-(1...)
Affinity DataIC50: 5.5nMAssay Description:The assay was performed in Perkin Elmer 384 well white Proxiplates in a total volume of 8 μl. 1 nM (fc)C-term myc tagged ACSS2 (human, recombina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2024
Entry Details
Go to US Patent

TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Merck Patent

US Patent
LigandPNGBDBM644900(US20240009175, Compound 8 | [7-chloro-3-ethyl-6-(1...)
Affinity DataIC50: 5.5nMAssay Description:The assay was performed in Perkin Elmer 384 well white Proxiplates in a total volume of 8 μl. 1 nM (fc)C-term myc tagged ACSS2 (human, recombina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2024
Entry Details
Go to US Patent