BDBM644513 5-((2-(4-((3- (cyanomethyl)- 5-(trifluoro- methoxy) benzyl) amino)butoxy) ethyl)amino) benzo[c][2,6] naphthyridine- 8- carboxylic acid::US11866436, Example 108

SMILES OC(=O)c1ccc2c(c1)nc(NCCOCCCCNCc1cc(CC#N)cc(OC(F)(F)F)c1)c1ccncc21

InChI Key InChIKey=SPXYVKFVIYDTRR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 644513   

TargetCasein kinase II subunit alpha [2-329](Human)
Cambridge Enterprise

US Patent
LigandPNGBDBM644513(US11866436, Example 108 | 5-((2-(4-((3- (cyanometh...)
Affinity DataIC50: 0.304nMAssay Description:Final assay conditions comprised 0.2 nM CK2α, 50 μM peptide substrate (RRRADDSDDDDD), 15 μM ATP in 1× reaction buffer (40 mM Tris pH7....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2024
Entry Details
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TargetDual specificity protein kinase CLK2(Human)
Cambridge Enterprise

US Patent
LigandPNGBDBM644513(US11866436, Example 108 | 5-((2-(4-((3- (cyanometh...)
Affinity DataIC50: 513nMAssay Description:The assay was conducted in the same way as described for CK2α, with final assay conditions comprising 20 nM CLK2 (Carna Biosciences-04-127), 50 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2024
Entry Details
Go to US Patent