BDBM644445 5-((2-(4-((3-cyano-4- cyclopropylbenzyl) amino)butoxy) ethyl)amino) benzo[c][2,6] naphthyridine- 8-carboxylic acid::US11866436, Example 39

SMILES OC(=O)c1ccc2c(c1)nc(NCCOCCCCNCc1ccc(C3CC3)c(c1)C#N)c1ccncc21

InChI Key InChIKey=UYTQWUKVIAOCJI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 644445   

TargetCasein kinase II subunit alpha [2-329](Human)
Cambridge Enterprise

US Patent
LigandPNGBDBM644445(US11866436, Example 39 | 5-((2-(4-((3-cyano-4- cyc...)
Affinity DataIC50: 0.197nMAssay Description:Final assay conditions comprised 0.2 nM CK2α, 50 μM peptide substrate (RRRADDSDDDDD), 15 μM ATP in 1× reaction buffer (40 mM Tris pH7....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2024
Entry Details
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TargetDual specificity protein kinase CLK2(Human)
Cambridge Enterprise

US Patent
LigandPNGBDBM644445(US11866436, Example 39 | 5-((2-(4-((3-cyano-4- cyc...)
Affinity DataIC50: 312nMAssay Description:The assay was conducted in the same way as described for CK2α, with final assay conditions comprising 20 nM CLK2 (Carna Biosciences-04-127), 50 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2024
Entry Details
Go to US Patent