BDBM644417 5-((2-(4-((3-chloro-4- (cyclopentyloxy) benzyl)amino) butoxy)ethyl) amino)benzo[c][2,6] naphthyridine- 8-carboxamide::US11866436, Example 11

SMILES NC(=O)c1ccc2c(c1)nc(NCCOCCCCNCc1ccc(OC3CCCC3)c(Cl)c1)c1ccncc21

InChI Key InChIKey=YMHQJLDBABXRTR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 644417   

TargetCasein kinase II subunit alpha [2-329](Human)
Cambridge Enterprise

US Patent
LigandPNGBDBM644417(US11866436, Example 11 | 5-((2-(4-((3-chloro-4- (c...)
Affinity DataIC50: 0.244nMAssay Description:Final assay conditions comprised 0.2 nM CK2α, 50 μM peptide substrate (RRRADDSDDDDD), 15 μM ATP in 1× reaction buffer (40 mM Tris pH7....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2024
Entry Details
Go to US Patent

TargetDual specificity protein kinase CLK2(Human)
Cambridge Enterprise

US Patent
LigandPNGBDBM644417(US11866436, Example 11 | 5-((2-(4-((3-chloro-4- (c...)
Affinity DataIC50: 749nMAssay Description:The assay was conducted in the same way as described for CK2α, with final assay conditions comprising 20 nM CLK2 (Carna Biosciences-04-127), 50 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2024
Entry Details
Go to US Patent