BDBM644392 6-chloro-1-methyl-4-{4-[(4-methylphenyl)methyl]piperazin-1-yl}-2-oxo-1,2-dihydro-1,5-naphthyridine-3-carbonitrile::US11866430, Example 386

SMILES Cc1ccc(CN2CCN(CC2)c2c(C#N)c(=O)n(C)c3ccc(Cl)nc23)cc1

InChI Key InChIKey=LVGHZVAUEFLYPR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 644392   

TargetDiacylglycerol kinase alpha(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM644392(US11866430, Example 386 | 6-chloro-1-methyl-4-{4-[...)
Affinity DataIC50: 150nMAssay Description:The compound inhibition studies were carried out as follows: 50 nL droplets of each test compound (top concentration 10 mM with 11 point, 3-fold dilu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2024
Entry Details
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TargetDiacylglycerol kinase zeta(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM644392(US11866430, Example 386 | 6-chloro-1-methyl-4-{4-[...)
Affinity DataIC50: 1.90E+5nMAssay Description:The compound inhibition studies were carried out as follows: 50 nL droplets of each test compound (top concentration 10 mM with 11 point, 3-fold dilu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2024
Entry Details
Go to US Patent