BDBM644248 4-(4-(4-fluoro-2-hydroxybenzyl)piperazin-1-yl)-1,6-dimethyl-2-oxo-1,2-dihydro-1,5-naphthyridine-3-carbonitrile::US11866430, Example 194

SMILES Cc1ccc2n(C)c(=O)c(C#N)c(N3CCN(Cc4ccc(F)cc4O)CC3)c2n1

InChI Key InChIKey=KWRJNURGYARAFN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 644248   

TargetDiacylglycerol kinase alpha(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM644248(US11866430, Example 194 | 4-(4-(4-fluoro-2-hydroxy...)
Affinity DataIC50: 76nMAssay Description:The compound inhibition studies were carried out as follows: 50 nL droplets of each test compound (top concentration 10 mM with 11 point, 3-fold dilu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2024
Entry Details
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TargetDiacylglycerol kinase zeta(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM644248(US11866430, Example 194 | 4-(4-(4-fluoro-2-hydroxy...)
Affinity DataIC50: 6.20E+4nMAssay Description:The compound inhibition studies were carried out as follows: 50 nL droplets of each test compound (top concentration 10 mM with 11 point, 3-fold dilu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2024
Entry Details
Go to US Patent