BDBM644175 6-bromo-4-(4-((4-fluorophenyl)(2-hydroxyphenyl)methyl)piperazin-1-yl)-1-methyl-3-nitro-1,5-naphthyridin-2(1H)-one::US11866430, Example 70

SMILES Cn1c2ccc(Br)nc2c(N2CCN(CC2)C(c2ccc(F)cc2)c2ccccc2O)c([N+]([O-])=O)c1=O

InChI Key InChIKey=PVCWDXVNDUUZCU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 644175   

TargetDiacylglycerol kinase alpha(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM644175(US11866430, Example 70 | 6-bromo-4-(4-((4-fluoroph...)
Affinity DataIC50: 130nMAssay Description:The compound inhibition studies were carried out as follows: 50 nL droplets of each test compound (top concentration 10 mM with 11 point, 3-fold dilu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2024
Entry Details
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TargetDiacylglycerol kinase zeta(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM644175(US11866430, Example 70 | 6-bromo-4-(4-((4-fluoroph...)
Affinity DataIC50: 3.30E+3nMAssay Description:The compound inhibition studies were carried out as follows: 50 nL droplets of each test compound (top concentration 10 mM with 11 point, 3-fold dilu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2024
Entry Details
Go to US Patent