BDBM644123 US11866430, Example 10

SMILES Cn1c2ccc(Br)nc2c(N2CCN(CC2)[C@@H](c2ccc(F)cc2)c2ccccc2O)c(C#N)c1=O

InChI Key InChIKey=AMFZLRHCQUBSJQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 644123   

TargetDiacylglycerol kinase alpha(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM644123(US11866430, Example 10)
Affinity DataIC50: 120nMAssay Description:The compound inhibition studies were carried out as follows: 50 nL droplets of each test compound (top concentration 10 mM with 11 point, 3-fold dilu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2024
Entry Details
Go to US Patent

TargetDiacylglycerol kinase zeta(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM644123(US11866430, Example 10)
Affinity DataIC50: 2.30E+4nMAssay Description:The compound inhibition studies were carried out as follows: 50 nL droplets of each test compound (top concentration 10 mM with 11 point, 3-fold dilu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2024
Entry Details
Go to US Patent