BDBM643925 US11866416, Compound SN-I-240j

SMILES NC(=O)c1ccccc1NC(=O)c1ccc(cc1)-c1ccccc1

InChI Key InChIKey=ZHLHOYCEJNEVGW-UHFFFAOYSA-N

Data  3 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 643925   

TargetBiofilm regulatory protein A(Streptococcus mutans serotype c (strain ATCC 70061...)
Uab Research Foundation

US Patent
LigandPNGBDBM643925(US11866416, Compound SN-I-240j)
Affinity DataIC50: 5.00E+5nMAssay Description:A previously reported zymographic assay was utilized for the investigation of Gtf enzymatic activity, as described in Example 1. A 1:100 in fresh 5 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2024
Entry Details
Go to US Patent

TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Henan University

Curated by ChEMBL
LigandPNGBDBM643925(US11866416, Compound SN-I-240j)
Affinity DataIC50: 2.78E+4nMAssay Description:Inhibition of human PD-1/PD-L1 interaction incubated for 24 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Henan University

Curated by ChEMBL
LigandPNGBDBM643925(US11866416, Compound SN-I-240j)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of PD-1/PD-L1 interaction (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetProgrammed cell death 1 ligand 1(Human)
Nantes University

Curated by ChEMBL
LigandPNGBDBM643925(US11866416, Compound SN-I-240j)
Affinity DataKd:  4.95E+4nMAssay Description:Binding affinity to CM5 sensor chip immobilized recombinant human PD-L1 ectodomain (18 to 239 residues) assessed as dissociation constant by SPR assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed