BDBM643277 US20240002388, Compound 79

SMILES CC(C)n1ncc2cnc(nc12)C(=O)NC1(CC1)c1ccc(cc1)-c1cncn(c1=O)C1(C)CCC1

InChI Key InChIKey=NEKHORBCWMPOQK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 643277   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Hutchison Medipharma

US Patent
LigandPNGBDBM643277(US20240002388, Compound 79)
Affinity DataIC50: 21nMAssay Description:ADP-Glo Kinase kit can be used to measure ADP level in kinase activity assay so as to distinguish the inhibitory effects of different compounds on RI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2024
Entry Details
Go to US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Hutchison Medipharma

US Patent
LigandPNGBDBM643277(US20240002388, Compound 79)
Affinity DataIC50: 10nMAssay Description:ADP-Glo Kinase kit can be used to measure ADP level in kinase activity assay so as to distinguish the inhibitory effects of different compounds on RI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2024
Entry Details
Go to US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Hutchison Medipharma

US Patent
LigandPNGBDBM643277(US20240002388, Compound 79)
Affinity DataIC50: 10nMAssay Description:ADP-Glo Kinase kit can be used to measure ADP level in kinase activity assay so as to distinguish the inhibitory effects of different compounds on RI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2024
Entry Details
Go to US Patent