BDBM643269 US20240002388, Compound 84::US20240002388, Compound 85

SMILES CC(C)n1ncc2cnc(nc12)C(=O)NC1(CC1)c1ccc(cc1)-c1cncn([C@H](C)C2CC2)c1=O

InChI Key InChIKey=BIYPCXFMNUSTID-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 643269   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Hutchison Medipharma

US Patent
LigandPNGBDBM643269(US20240002388, Compound 85 | US20240002388, Compou...)
Affinity DataIC50: 45nMAssay Description:ADP-Glo Kinase kit can be used to measure ADP level in kinase activity assay so as to distinguish the inhibitory effects of different compounds on RI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2024
Entry Details
Go to US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Hutchison Medipharma

US Patent
LigandPNGBDBM643269(US20240002388, Compound 85 | US20240002388, Compou...)
Affinity DataIC50: 30nMAssay Description:ADP-Glo Kinase kit can be used to measure ADP level in kinase activity assay so as to distinguish the inhibitory effects of different compounds on RI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2024
Entry Details
Go to US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Hutchison Medipharma

US Patent
LigandPNGBDBM643269(US20240002388, Compound 85 | US20240002388, Compou...)
Affinity DataIC50: 5nMAssay Description:ADP-Glo Kinase kit can be used to measure ADP level in kinase activity assay so as to distinguish the inhibitory effects of different compounds on RI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2024
Entry Details
Go to US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Hutchison Medipharma

US Patent
LigandPNGBDBM643269(US20240002388, Compound 85 | US20240002388, Compou...)
Affinity DataIC50: 5nMAssay Description:ADP-Glo Kinase kit can be used to measure ADP level in kinase activity assay so as to distinguish the inhibitory effects of different compounds on RI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2024
Entry Details
Go to US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Hutchison Medipharma

US Patent
LigandPNGBDBM643269(US20240002388, Compound 85 | US20240002388, Compou...)
Affinity DataIC50: 5nMAssay Description:ADP-Glo Kinase kit can be used to measure ADP level in kinase activity assay so as to distinguish the inhibitory effects of different compounds on RI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2024
Entry Details
Go to US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Hutchison Medipharma

US Patent
LigandPNGBDBM643269(US20240002388, Compound 85 | US20240002388, Compou...)
Affinity DataIC50: 5nMAssay Description:ADP-Glo Kinase kit can be used to measure ADP level in kinase activity assay so as to distinguish the inhibitory effects of different compounds on RI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2024
Entry Details
Go to US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Hutchison Medipharma

US Patent
LigandPNGBDBM643269(US20240002388, Compound 85 | US20240002388, Compou...)
Affinity DataIC50: 5nMAssay Description:ADP-Glo Kinase kit can be used to measure ADP level in kinase activity assay so as to distinguish the inhibitory effects of different compounds on RI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2024
Entry Details
Go to US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Hutchison Medipharma

US Patent
LigandPNGBDBM643269(US20240002388, Compound 85 | US20240002388, Compou...)
Affinity DataIC50: 5nMAssay Description:ADP-Glo Kinase kit can be used to measure ADP level in kinase activity assay so as to distinguish the inhibitory effects of different compounds on RI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2024
Entry Details
Go to US Patent