BDBM643258 US20240002388, Compound 15::US20240002388, Compound 16

SMILES CC(C)n1cncc(-c2ccc(cc2)C2(CC2)NC(=O)c2nc3CC[C@H](c4ccccc4)n3n2)c1=O

InChI Key InChIKey=ZDLMQKSBLDHTAJ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 643258   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Hutchison Medipharma

US Patent
LigandPNGBDBM643258(US20240002388, Compound 16 | US20240002388, Compou...)
Affinity DataIC50: 30nMAssay Description:ADP-Glo Kinase kit can be used to measure ADP level in kinase activity assay so as to distinguish the inhibitory effects of different compounds on RI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2024
Entry Details
Go to US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Hutchison Medipharma

US Patent
LigandPNGBDBM643258(US20240002388, Compound 16 | US20240002388, Compou...)
Affinity DataIC50: 25nMAssay Description:ADP-Glo Kinase kit can be used to measure ADP level in kinase activity assay so as to distinguish the inhibitory effects of different compounds on RI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2024
Entry Details
Go to US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Hutchison Medipharma

US Patent
LigandPNGBDBM643258(US20240002388, Compound 16 | US20240002388, Compou...)
Affinity DataIC50: 2.37E+3nMAssay Description:ADP-Glo Kinase kit can be used to measure ADP level in kinase activity assay so as to distinguish the inhibitory effects of different compounds on RI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2024
Entry Details
Go to US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Hutchison Medipharma

US Patent
LigandPNGBDBM643258(US20240002388, Compound 16 | US20240002388, Compou...)
Affinity DataIC50: 7nMAssay Description:ADP-Glo Kinase kit can be used to measure ADP level in kinase activity assay so as to distinguish the inhibitory effects of different compounds on RI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2024
Entry Details
Go to US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Hutchison Medipharma

US Patent
LigandPNGBDBM643258(US20240002388, Compound 16 | US20240002388, Compou...)
Affinity DataIC50: 2.37E+3nMAssay Description:ADP-Glo Kinase kit can be used to measure ADP level in kinase activity assay so as to distinguish the inhibitory effects of different compounds on RI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2024
Entry Details
Go to US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Hutchison Medipharma

US Patent
LigandPNGBDBM643258(US20240002388, Compound 16 | US20240002388, Compou...)
Affinity DataIC50: 7nMAssay Description:ADP-Glo Kinase kit can be used to measure ADP level in kinase activity assay so as to distinguish the inhibitory effects of different compounds on RI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2024
Entry Details
Go to US Patent