BDBM643118 US20240002339, Example 55

SMILES c1ccc2c(c1)c(c[nH]2)CCNc3ccc(cc3C(=O)O)OC(F)(F)F

InChI Key InChIKey=JBKMTXNTOPCVOT-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 643118   

TargetCyclin-dependent kinase 2(Human)
University of Minnesota

US Patent
LigandPNGBDBM643118(US20240002339, Example 55)
Affinity DataIC50: 940nMAssay Description:CDK2 was thawed at room temperature and buffer exchanged using Zeba spin desalting columns. The final ITC buffer was 1×PBS, 10 mM MgCl2, and 5% glyce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2024
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetCyclin-dependent kinase 2(Human)
University of Minnesota

US Patent
LigandPNGBDBM643118(US20240002339, Example 55)
Affinity DataIC50: 940nMAssay Description:Inhibition of 8-((4-chlorophenyl)amino)naphthalene-1-sulfonic acid binding to CDK2 (unknown origin) measured after 2 hrs by fluorescence based analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)