BDBM642981 US20240000767, Example 106::US20240000767, Example 107::US20240000767, Example 59::rac-N-[(3,5-Difluoropyridin-2-yl)methyl]-2-{3-[(2,2,2-trifluoroethoxy)methyl][1,4′-bipiperidin]-1′-yl}-1,3-thiazole-5-carboxamide

SMILES Fc1cnc(CNC(=O)c2cnc(s2)N2CCC(CC2)N2CCCC(COCC(F)(F)F)C2)c(F)c1

InChI Key InChIKey=MGVMZZPBXYYHDX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 642981   

TargetAlpha-2C adrenergic receptor(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM642981(rac-N-[(3,5-Difluoropyridin-2-yl)methyl]-2-{3-[(2,...)
Affinity DataIC50: 11nMAssay Description:In Vitro Radioligand Binding Studies for Determination of the Dissociation Constants K1 at the Human Adrenoreceptor ADRA2C (Eurofins Panlabs Discover...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2024
Entry Details
Go to US Patent

TargetAlpha-2C adrenergic receptor(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM642981(rac-N-[(3,5-Difluoropyridin-2-yl)methyl]-2-{3-[(2,...)
Affinity DataIC50: 0.5nMAssay Description:In Vitro Radioligand Binding Studies for Determination of the Dissociation Constants K1 at the Human Adrenoreceptor ADRA2C (Eurofins Panlabs Discover...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2024
Entry Details
Go to US Patent

TargetAlpha-2C adrenergic receptor(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM642981(rac-N-[(3,5-Difluoropyridin-2-yl)methyl]-2-{3-[(2,...)
Affinity DataIC50: 37nMAssay Description:In Vitro Radioligand Binding Studies for Determination of the Dissociation Constants K1 at the Human Adrenoreceptor ADRA2C (Eurofins Panlabs Discover...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2024
Entry Details
Go to US Patent