BDBM642929 2-[3-(Cyclopropylmethyl)[1,4′-bipiperidin]-1′-yl]-N-[(3,5-difluoropyridin-2-yl)methyl]-1,3-thiazole-5-carboxamide (racemate)::US20240000767, Example 3

SMILES Fc1cnc(CNC(=O)c2cnc(s2)N2CCC(CC2)N2CCCC(CC3CC3)C2)c(F)c1

InChI Key InChIKey=SJYFHRUFDMNIGL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 642929   

TargetAlpha-2C adrenergic receptor(Human)
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US Patent
LigandPNGBDBM642929(US20240000767, Example 3 | 2-[3-(Cyclopropylmethyl...)
Affinity DataIC50: 2.90nMAssay Description:In Vitro Radioligand Binding Studies for Determination of the Dissociation Constants K1 at the Human Adrenoreceptor ADRA2C (Eurofins Panlabs Discover...More data for this Ligand-Target Pair
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Date in BDB:
2/28/2024
Entry Details
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