BDBM642847 US11858905, Compound 47

SMILES CC1(CC1)c1cc(C(=O)N[C@@H](Cc2nc3ccc(cc3o2)-c2ccnc(c2)C(F)F)C(=O)NC2(CC2)C#N)n(n1)C1CC1

InChI Key InChIKey=HFFRGGRSRCNTTF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 642847   

TargetProcathepsin L(Human)
Biofront Therapeutics (Beijing) Co.

US Patent
LigandPNGBDBM642847(US11858905, Compound 47)
Affinity DataIC50: 6.60nMAssay Description:Human cathepsin L enzymatic assay was performed in assay buffer (50 mM MES pH 5.5, 2.5 mM DTT, 0.5 mM EDTA) to assess the inhibition of human CatL by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2024
Entry Details
Go to US Patent