BDBM642842 US11858905, Compound 42

SMILES Cc1ccc(cn1)-c1ccc2nc(C[C@H](NC(=O)c3cc(nn3C3CC3)C3(C)CC3)C(=O)NC3(CC3)C#N)oc2c1

InChI Key InChIKey=PYTGNWADIAKWOT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 642842   

TargetProcathepsin L(Human)
Biofront Therapeutics (Beijing) Co.

US Patent
LigandPNGBDBM642842(US11858905, Compound 42)
Affinity DataIC50: 4.5nMAssay Description:Human cathepsin L enzymatic assay was performed in assay buffer (50 mM MES pH 5.5, 2.5 mM DTT, 0.5 mM EDTA) to assess the inhibition of human CatL by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2024
Entry Details
Go to US Patent