BDBM64280 5-chloranyl-2-[(4-fluorophenyl)methylsulfonyl]-N-(5-propan-2-yl-1,3,4-thiadiazol-2-yl)pyrimidine-4-carboxamide::5-chloro-2-(4-fluorobenzyl)sulfonyl-N-(5-isopropyl-1,3,4-thiadiazol-2-yl)pyrimidine-4-carboxamide::5-chloro-2-[(4-fluorophenyl)methylsulfonyl]-N-(5-propan-2-yl-1,3,4-thiadiazol-2-yl)-4-pyrimidinecarboxamide::5-chloro-2-[(4-fluorophenyl)methylsulfonyl]-N-(5-propan-2-yl-1,3,4-thiadiazol-2-yl)pyrimidine-4-carboxamide::MLS001116206::SMR000625775::cid_16446399

SMILES CC(C)c1nnc(NC(=O)c2nc(ncc2Cl)S(=O)(=O)Cc2ccc(F)cc2)s1

InChI Key InChIKey=LFJWSGCNKPRHNB-UHFFFAOYSA-N

Data  4 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 64280   

TargetHeat shock factor protein 1(Mouse)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM64280(SMR000625775 | MLS001116206 | cid_16446399 | 5-chl...)
Affinity DataEC50:  3.33E+3nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2011
Entry Details
PCBioAssay
TargetPotassium voltage-gated channel subfamily KQT member 2(Rat)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM64280(SMR000625775 | MLS001116206 | cid_16446399 | 5-chl...)
Affinity DataEC50:  4.47E+3nMAssay Description:BioAssay Type: Confirmatory, Concentration-Response Relationship Observed Source (MLPCN Center Name): Johns Hopkins Ion Channel Center (JHICC) Center...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2011
Entry Details
PCBioAssay
TargetProtein RecA(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Southern Research Specialized Biocontainment Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM64280(SMR000625775 | MLS001116206 | cid_16446399 | 5-chl...)
Affinity DataIC50: 5.38E+4nMAssay Description:Southern Research's Specialized Biocontainment Screening Center (SRSBSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Librarie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2011
Entry Details
PCBioAssay
TargetHepatocyte nuclear factor 4-alpha(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM64280(SMR000625775 | MLS001116206 | cid_16446399 | 5-chl...)
Affinity DataIC50: 4.69E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2013
Entry Details
PCBioAssay
TargetPerilipin-1(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM64280(SMR000625775 | MLS001116206 | cid_16446399 | 5-chl...)
Affinity DataIC50: 2.84E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2013
Entry Details
PCBioAssay
TargetPerilipin-5(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM64280(SMR000625775 | MLS001116206 | cid_16446399 | 5-chl...)
Affinity DataIC50: 1.94E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2013
Entry Details
PCBioAssay
TargetTumor necrosis factor receptor superfamily member 10B(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM64280(SMR000625775 | MLS001116206 | cid_16446399 | 5-chl...)
Affinity DataEC50: >1.25E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2013
Entry Details
PCBioAssay