BDBM642602 (2R,3'R)-N-(3-(2-((3-meth- oxy-1-methyl-1H-py- razol-4-yl)amino)-5- methylpyrimidin-4-yl)- 1H-indol-7-yl)-1'-meth- yl-[1,3'-bipyrrolidine]- 2-carboxamide::US20230416237, Example 28::US20230416237, Example 29
SMILES COc1nn(C)cc1Nc1ncc(C)c(n1)-c1c[nH]c2c(NC(=O)C3CCCN3C3CCN(C)C3)cccc12
InChI Key InChIKey=NVGGUHXZVUUUNM-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 642602
Affinity DataIC50: 40nMAssay Description:The inhibitory activity (IC50) of the amide compound for JAK1 and JAK2 under 1 mM ATP was measured by a mobility shift assay method. JAK1 was purchas...More data for this Ligand-Target Pair
Affinity DataIC50: 1.63E+4nMAssay Description:The inhibitory activity (IC50) of the amide compound for JAK1 and JAK2 under 1 mM ATP was measured by a mobility shift assay method. JAK1 was purchas...More data for this Ligand-Target Pair
Affinity DataIC50: 67nMAssay Description:The inhibitory activity (IC50) of the amide compound for JAK1 and JAK2 under 1 mM ATP was measured by a mobility shift assay method. JAK1 was purchas...More data for this Ligand-Target Pair
Affinity DataIC50: 1.34E+4nMAssay Description:The inhibitory activity (IC50) of the amide compound for JAK1 and JAK2 under 1 mM ATP was measured by a mobility shift assay method. JAK1 was purchas...More data for this Ligand-Target Pair