BDBM642309 (+)-(R)-(5-amino-5-(1-(2-oxo-2-(prop-2- yn-1-ylamino)ethyl)-1H-tetrazol-5- yl)pentyl)boronic acid::US11845767, Example 355

SMILES N[C@H](CCCCB(O)O)c1nnnn1CC(=O)NCC#C

InChI Key InChIKey=KGEPAUWCNQIQHK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 642309   

TargetArginase-1(Human)
Rijksuniversiteit Groningen

US Patent
LigandPNGBDBM642309((+)-(R)-(5-amino-5-(1-(2-oxo-2-(prop-2- yn-1-ylami...)
Affinity DataIC50: 15nMAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARGG II) novel compounds is followed spectrophotometrically at 530 nm. The compound to be tested is...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2024
Entry Details
Go to US Patent

TargetArginase-2, mitochondrial(Human)
Rijksuniversiteit Groningen

US Patent
LigandPNGBDBM642309((+)-(R)-(5-amino-5-(1-(2-oxo-2-(prop-2- yn-1-ylami...)
Affinity DataIC50: 30nMAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARGG II) novel compounds is followed spectrophotometrically at 530 nm. The compound to be tested is...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2024
Entry Details
Go to US Patent