BDBM642187 US11845740, No II::US20240116898, No II

SMILES O=C(NCCc1cnc[nH]1)c1cccc(c1)C(=O)NCCc1cnc[nH]1

InChI Key InChIKey=ROSNIOAWJWZICE-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 642187   

TargetGlutaminyl-peptide cyclotransferase(Human)
Ltd “Valenta-Intellekt”

US Patent
LigandPNGBDBM642187(US11845740, No II | US20240116898, No II)
Affinity DataIC50: 2.90E+3nMAssay Description:The glutaminyl cyclase activity at various concentrations of Compounds I-X has been studied at 25 C. with the use of a fluorescent substrate L-glutam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2024
Entry Details
Go to US Patent

TargetGlutaminyl-peptide cyclotransferase(Human)
Ltd “Valenta-Intellekt”

US Patent
LigandPNGBDBM642187(US11845740, No II | US20240116898, No II)
Affinity DataIC50: 2.90E+3nMAssay Description:During studies of the effect of Compounds I-X, which are the object of the present invention, on the enzymatic activity of glutaminyl cyclase in vitr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
Go to US Patent

TargetGlutaminyl-peptide cyclotransferase(Human)
Ltd “Valenta-Intellekt”

US Patent
LigandPNGBDBM642187(US11845740, No II | US20240116898, No II)
Affinity DataKi:  1.61E+3nMAssay Description:The glutaminyl cyclase activity at various concentrations of Compounds I-X has been studied at 25 C. with the use of a fluorescent substrate L-glutam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2024
Entry Details
Go to US Patent

TargetGlutaminyl-peptide cyclotransferase(Human)
Ltd “Valenta-Intellekt”

US Patent
LigandPNGBDBM642187(US11845740, No II | US20240116898, No II)
Affinity DataKi:  1.61E+3nMAssay Description:During studies of the effect of Compounds I-X, which are the object of the present invention, on the enzymatic activity of glutaminyl cyclase in vitr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
Go to US Patent