BDBM642121 US11845730, Example 49

SMILES COc1c(F)cc(O[C@H]2C[C@@H](C2)NCc2c(F)ccc3cnccc23)cc1F

InChI Key InChIKey=BNIJAFGWAGTCPM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 642121   

LigandPNGBDBM642121(US11845730, Example 49)
Affinity DataIC50: 16.3nMAssay Description:Assay buffer preparation: 1 HBSS, 2 mM HEPES, 0.1% BSA plus 2.5 mM freshly prepared probenecid (Invitrogen, #P36400). 25 μl/well assay buffer in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2024
Entry Details
US Patent