BDBM642119 US11845730, Example 47

SMILES OCc1cc(F)c(CN[C@H]2C[C@@H](C2)Oc2ccc3OC(F)(F)Oc3c2)c2ccncc12

InChI Key InChIKey=QCTONOHPHAVNMS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 642119   

LigandPNGBDBM642119(US11845730, Example 47)
Affinity DataIC50: 23.8nMAssay Description:Assay buffer preparation: 1 HBSS, 2 mM HEPES, 0.1% BSA plus 2.5 mM freshly prepared probenecid (Invitrogen, #P36400). 25 μl/well assay buffer in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2024
Entry Details
US Patent