BDBM641580 US11845723, Example 476

SMILES CN(c1cccc(c1)-c1ccc(NC(=O)C(C)(C)C)cc1)c1nc2nncn2c2cc(Cl)ccc12

InChI Key InChIKey=WIQRBXQGVWQUDI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 641580   

TargetDiacylglycerol kinase alpha(Human)
Gilead Sciences

US Patent
LigandPNGBDBM641580(US11845723, Example 476)
Affinity DataIC50: 5.60nMAssay Description:Table 6: Alternatively, the enzymatic activity of human DGKα was monitored in a biochemical assay in the presence or absence of compounds and us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2024
Entry Details
Go to US Patent