BDBM641555 US11845723, Example 451

SMILES CN(c1cccc(c1)-c1cnc(cn1)C1CC1)c1nc2nncn2c2cc(Cl)c(F)cc12

InChI Key InChIKey=SYEQRFZOKBJAET-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 641555   

TargetDiacylglycerol kinase alpha(Human)
Gilead Sciences

US Patent
LigandPNGBDBM641555(US11845723, Example 451)
Affinity DataIC50: 4.5nMAssay Description:Table 6: Alternatively, the enzymatic activity of human DGKα was monitored in a biochemical assay in the presence or absence of compounds and us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2024
Entry Details
Go to US Patent