BDBM6413 (3-Chloro-phenyl)-{6-[5-(3-phenyl-propylamino)-pyridin-3-yl]-pyrazin-2-yl}-amine::N-(3-chlorophenyl)-6-{5-[(3-phenylpropyl)amino]pyridin-3-yl}pyrazin-2-amine::Pyrazine-Pyridine Biheteroaryl 59

SMILES Clc1cccc(Nc2cncc(n2)-c2cncc(NCCCc3ccccc3)c2)c1

InChI Key InChIKey=NNTGNPPBTNKLPC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 6413   

TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6413(N-(3-chlorophenyl)-6-{5-[(3-phenylpropyl)amino]pyr...)
Affinity DataIC50: 1.00E+4nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2005
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Rat)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6413(N-(3-chlorophenyl)-6-{5-[(3-phenylpropyl)amino]pyr...)
Affinity DataIC50: 2.28E+3nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2005
Entry Details Article
PubMed