BDBM6411 N-(3-Chlorophenyl)-6-[5-[[(tetrahydro-2H-pyran-4-yl)-methyl]amino]-3-pyridinyl]-2-pyrazinamine::N-(3-chlorophenyl)-6-{5-[(oxan-4-ylmethyl)amino]pyridin-3-yl}pyrazin-2-amine::Pyrazine-Pyridine Biheteroaryl 54

SMILES Clc1cccc(Nc2cncc(n2)-c2cncc(NCC3CCOCC3)c2)c1

InChI Key InChIKey=ALEMXOWDMCVYMB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 6411   

TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6411(N-(3-chlorophenyl)-6-{5-[(oxan-4-ylmethyl)amino]py...)
Affinity DataIC50: 1.00E+4nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2005
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Rat)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6411(N-(3-chlorophenyl)-6-{5-[(oxan-4-ylmethyl)amino]py...)
Affinity DataIC50: 391nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2005
Entry Details Article
PubMed