BDBM640923 4-(8-((1S,2S,4R)-2-amino-7-azabicyclo[2.2.1]heptane-7-yl)-3-(6-fluoro-1-(2-hydroxy-2-methylpropyl)-1H-benzo[d][1,2,3]triazol-5-yl)imidazo[1,2-a]pyrazin-2-yl)-2-fluorobenzonitrile ::US20230399332, Compound 27

SMILES CC(C)(O)Cn1nnc2cc(-c3c(nc4c(nccn34)N3[C@@H]4CC[C@H]3[C@@H](N)C4)-c3ccc(C#N)c(F)c3)c(F)cc12

InChI Key InChIKey=LDNPHMRRYHAHTR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 640923   

TargetLysine-specific histone demethylase 1A(Human)
Tencent Technology (Shenzhen)

US Patent
LigandPNGBDBM640923(4-(8-((1S,2S,4R)-2-amino-7-azabicyclo[2.2.1]heptan...)
Affinity DataIC50: 1nMAssay Description:Experimental steps and a method: In this experiment, the in vitro inhibitory activity of the compounds of the present disclosure against LSD1 on an e...More data for this Ligand-Target Pair
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Date in BDB:
2/3/2024
Entry Details
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