BDBM640921 (S)-4-(8-(3-aminopiperidin-1-yl)-3-(6-fluoro-1-(2-hydroxy-2-methylpropyl)-1H-benzo[d][1,2,3]triazol-5-yl)imidazo[1,2-a]pyrazin-2-yl)-2-fluorobenzonitrile ::US20230399332, Compound 23

SMILES CC(C)(O)Cn1nnc2cc(-c3c(nc4c(nccn34)N3CCC[C@H](N)C3)-c3ccc(C#N)c(F)c3)c(F)cc12

InChI Key InChIKey=WHWMUOJYHRWTCV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 640921   

TargetLysine-specific histone demethylase 1A(Human)
Tencent Technology (Shenzhen)

US Patent
LigandPNGBDBM640921((S)-4-(8-(3-aminopiperidin-1-yl)-3-(6-fluoro-1-(2-...)
Affinity DataIC50: 4.40nMAssay Description:Experimental steps and a method: In this experiment, the in vitro inhibitory activity of the compounds of the present disclosure against LSD1 on an e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2024
Entry Details
Go to US Patent