BDBM640915 (R)-4-(8-(3-aminopiperidin-1-yl)-3-(2-methyll-2H-indazol-5-yl)imidazo [1,2-a]pyrazin-2-yl)-2-fluorobenzonitrile ::US20230399332, Compound 17

SMILES Cn1cc2cc(ccc2n1)-c1c(nc2c(nccn12)N1CCC[C@@H](N)C1)-c1ccc(C#N)c(F)c1

InChI Key InChIKey=AJZBMRGRSMCZNS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 640915   

TargetLysine-specific histone demethylase 1A(Human)
Tencent Technology (Shenzhen)

US Patent
LigandPNGBDBM640915((R)-4-(8-(3-aminopiperidin-1-yl)-3-(2-methyll-2H-i...)
Affinity DataIC50: 6.30nMAssay Description:Experimental steps and a method: In this experiment, the in vitro inhibitory activity of the compounds of the present disclosure against LSD1 on an e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2024
Entry Details
Go to US Patent