BDBM640913 US20230399332, Compound 15::trans-4-(8-(((1R,3R)-3-aminocyclopentyl)amino)-3-(3-fluoro-4-methoxyphenyl)imidazo[1,2-a]pyrazin-2-yl)-2-fluorobenzonitrile

SMILES COc1ccc(cc1F)-c1c(nc2c(N[C@@H]3CC[C@@H](N)C3)nccn12)-c1ccc(C#N)c(F)c1

InChI Key InChIKey=FKEQTNUCNWKDME-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 640913   

TargetLysine-specific histone demethylase 1A(Human)
Tencent Technology (Shenzhen)

US Patent
LigandPNGBDBM640913(trans-4-(8-(((1R,3R)-3-aminocyclopentyl)amino)-3-(...)
Affinity DataIC50: 11nMAssay Description:Experimental steps and a method: In this experiment, the in vitro inhibitory activity of the compounds of the present disclosure against LSD1 on an e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2024
Entry Details
Go to US Patent