BDBM640885 US20230399327, Example 103::US20230399327, Example 99

SMILES COc1nc2CCN(C)Cc2cc1Nc1ncc2ccnc(N[C@@H]3CCC[C@H]3O)c2n1

InChI Key InChIKey=UWBUZQOMODMARP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 640885   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Adlai Nortye Biopharma Co.

US Patent
LigandPNGBDBM640885(US20230399327, Example 103 | US20230399327, Exampl...)
Affinity DataIC50: 0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2024
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Adlai Nortye Biopharma Co.

US Patent
LigandPNGBDBM640885(US20230399327, Example 103 | US20230399327, Exampl...)
Affinity DataIC50: 0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2024
Entry Details
Go to US Patent