BDBM640630 US20230399319, Example 2-182

SMILES CCCCC(=O)N1CCCN(CC1)S(=O)(=O)NC(=O)c1coc(Nc2cc(ccc2C)C(F)(F)F)n1

InChI Key InChIKey=SBOICAOKMKFLOG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 640630   

TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Japan Tobacco

US Patent
LigandPNGBDBM640630(US20230399319, Example 2-182)
Affinity DataIC50: 10nMAssay Description:The NLRP3 inflammasome inhibitory activity of test compounds were evaluated CM the basis of the inhibitory activity of the IL-1β, production in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2024
Entry Details
Go to US Patent