BDBM640364 Preparation of 3-((4-amino-7-ethyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)ethynyl)-4-methyl-N-(3-(trifluoromethyl)phenyl)benzamide ::US11840535, Example 6

SMILES CCn1cc(C#Cc2cc(ccc2C)C(=O)Nc2cccc(c2)C(F)(F)F)c2c(N)ncnc12

InChI Key InChIKey=IVQQGZRJCZWGPF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 640364   

TargetTyrosine-protein kinase ABL1(Human)
Shenzhen Targetrx

US Patent
LigandPNGBDBM640364(Preparation of 3-((4-amino-7-ethyl-7H-pyrrolo[2,3-...)
Affinity DataIC50: 5nMAssay Description:Specific Assay Method:Compound formulation: The test compounds were dissolved in DMSO to prepare a 20 mM stock solution. Before use, the compounds we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2024
Entry Details
Go to US Patent

TargetTyrosine-protein kinase ABL1 [T315I](Human)
Shenzhen Targetrx

US Patent
LigandPNGBDBM640364(Preparation of 3-((4-amino-7-ethyl-7H-pyrrolo[2,3-...)
Affinity DataIC50: 5nMAssay Description:Specific Assay Method:Compound formulation: The test compounds were dissolved in DMSO to prepare a 20 mM stock solution. Before use, the compounds we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2024
Entry Details
Go to US Patent