BDBM640355 8-amino-N-(2-methoxyethyl)-5-(4-(1- (2-methoxyethyl)-1H-pyrazole-4- yl)phenyl)-N-methyl-1,7- naphthyridine-3-carboxamide::US11840531, Compound 3.57

SMILES COCCN(C)C(=O)c1cnc2c(N)ncc(-c3ccc(cc3)-c3cnn(CCOC)c3)c2c1

InChI Key InChIKey=UYDAEDUHRFIAPX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 640355   

TargetCyclin-C/Cyclin-dependent kinase 8(Human)
Joint Stock Company “Biocad”

US Patent
LigandPNGBDBM640355(8-amino-N-(2-methoxyethyl)-5-(4-(1- (2-methoxyethy...)
Affinity DataIC50: 2.27nMAssay Description:Capability of compounds of the present invention to bind to CDK8 protein was detected using LanthaScreen (ThermoFisher) assay. We detected FRET signa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2024
Entry Details
Go to US Patent