BDBM640347 2-(4-(4-(8-amino-3-(4- methylpiperazine-1-carbonyl)-1,7- naphthyridine-5-yl)phenyl) -1H- pyrazole-1-yl)-N,N-dimethylacetamide::US11840531, Compound 3.49

SMILES CN(C)C(=O)Cn1cc(cn1)-c1ccc(cc1)-c1cnc(N)c2ncc(cc12)C(=O)N1CCN(C)CC1

InChI Key InChIKey=VECVCWNCMJVVMM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 640347   

TargetCyclin-C/Cyclin-dependent kinase 8(Human)
Joint Stock Company “Biocad”

US Patent
LigandPNGBDBM640347(2-(4-(4-(8-amino-3-(4- methylpiperazine-1-carbonyl...)
Affinity DataIC50: 1.85nMAssay Description:Capability of compounds of the present invention to bind to CDK8 protein was detected using LanthaScreen (ThermoFisher) assay. We detected FRET signa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2024
Entry Details
Go to US Patent