BDBM639408 ({bicyclo[1.1.1]pentan- 1-yl}methyl)({2-[(4- {6- methoxyimidazo[1,5- a]pyridin-8-yl}-1H- 1,2,3-triazol-1- yl)methyl]imidazo [1,2-a]pyridin-6- yl}methyl)amine::US20230391770, Example 28

SMILES COc1cc(-c2cn(Cc3cn4cc(CNCC56CC(C5)C6)ccc4n3)nn2)c2cncn2c1

InChI Key InChIKey=XYHNMVCKQISMBP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 639408   

LigandPNGBDBM639408(({bicyclo[1.1.1]pentan- 1-yl}methyl)({2-[(4- {6- m...)
Affinity DataIC50: 6.10nMAssay Description:The enzymatic assay was established to determine IC50 values for inhibition of RNA methyltransferase activity. The enzyme used was full-length his-ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
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TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM639408(({bicyclo[1.1.1]pentan- 1-yl}methyl)({2-[(4- {6- m...)
Affinity DataIC50: 6.10nMAssay Description:Inhibition of full-length His-tagged METTL3/full length FLAG-tagged METTL14 (unknown origin) expressed in baculovirus expression system using synthet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed