BDBM639381 US20230391768, Compound I-25

SMILES CCN1CCN(Cc2cc(NC(=O)c3ccc(C)c(c3)-c3ccc4nc(NC(=O)C5CC5)n(C)c4c3)cc(c2)C(F)(F)F)CC1

InChI Key InChIKey=KHUFHQSTBBHIHO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 639381   

TargetTyrosine-protein kinase JAK2(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM639381(US20230391768, Compound I-25)
Affinity DataIC50: 7.02E+3nMAssay Description:The JAK2 Z-Lyte biochemical assay was performed according to manufacturer's instructions (Life Technologies).More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
Go to US Patent